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The world's first & only sterile CBD for IV Infusion:
Gives your body peak access to the many potential benefits of cannabinoids
Administered through an IV, so your body is able to absorb nearly 100% of the dose
All natural, extracted from hemp grown in the USA
Contains zero THC
Sterile and safe for IV injection
Not psychoactive: It cannot get you high
Completely legal in the US
Rigorously third-party tested for potency and certified free of pesticides, microbials, mycotoxins, heavy metals and other possible contaminants
The endocannabinoid system (ECS) is a complex network of receptors and chemicals in your body that helps keep things in balance, like temperature, mood, appetite, and pain levels.
Think of it like a regulation system, like the thermostat in your home which helps maintain a comfortable environment.
Your body naturally produces substances called endocannabinoids, which are similar to compounds found in cannabis (like THC and CBD).
When your body needs help with something (like dealing with stress, feeling pain, or needing energy), the ECS helps your body respond by releasing these endocan abinoids, which work with the receptors to bring things back to normal.
So, it's like an invisible system that helps keep everything
running smoothly, even if you don't always notice it.
Unfortunately, this system is not always functioning at its best,
and, you can be deficient in endocannabinoids.
Furthermore, illness or stress may overwhelm
your body's ability to keep up with production.
This is why CBD supplementation can
be so useful in a variety of situations.
The cannabis plant, which humans have been
using for about 5,000 years, essentially works its
effects by hijacking the ancient cellular ECS
machinery!
When cannabinoids are absorbed into the body,
they bind to receptors and are able to exert many
and varied beneficial effects.
Here are some key functions of CB1 receptors:
1. Regulation of neurotransmitter release:
Affecting mood, cognition, and behavior.
2. Pain modulation: Involved in reducing pain
perception.
3. Appetite and metabolism: Can stimulate
appetite, and have roles in regulating energy
balance and metabolism.
4. Memory and learning: Can affect short-term
memory and contribute to the formation of new
memories.
5. Mood regulation: Linked to mood and emotional
regulation. They are thought to influence
anxiety, depression, and stress responses.
6. Motor control: CB1 receptors are found in areas
of the brain responsible for motor coordination,
so they help in controlling movement and
muscle function
While CB1 receptors are mainly associated with the central nervous system,
CB2 receptors have more of an effect on immune function and inflammation.
Here are the main functions of CB2 receptors:
1. Immune system modulation: CB2 receptors arefound on immune cells such as T-cells, B-cells,macrophages, and dendritic cells.
When activated, they can help regulate immuneresponses, potentially reducing inflammation and immune system activation.
This can be helpful in conditions involving chronic inflammation or autoimmune diseases.
2. Anti-inflammatory effects: CB2 receptor activation has been shown to play a role in reducing inflammation.
This is one reason why cannabinoids (like CBD) have been researched for their potential to treat conditions like arthritis, Crohn's disease, and other inflammatory disorders.
3. Pain management: By reducing inflammation, CB2 receptor activation can help alleviate pain, especially chronic or inflammatory pain.
4. Neuroprotection: Research suggests that CB2 activation might have neuroprotective effects, meaning it could help protect neurons from damage due to conditions like neurodegenerative diseases (e.g., Alzheimer's or Parkinson's disease).
5. Bone health: CB2 receptors are present in bone
become very popular to aid in the relief of a wide variety of symptoms.
• Topical CBD: Bioavailability is generally considered low (Less
than 10% absorbed).
The skin acts as a barrier, limiting theamount of CBD that can penetrate deeply enough to enter the bloodstream.
Only a small fraction of the CBD will pass through the skin, and even less will make it into the bloodstream.
It may be effective for localized issues like inflammation, pain, or
skin conditions, but it doesn't generally provide the systemic effects (like mood enhancement or anxiety reduction).
• Oral CBD (Ex: oils, capsule or edibles) Bioavailability is low to
moderate, typically ranging from 6%-20%.
This is because when you ingest CBD it goes to the liver where a significant portion of it is broken down (metabolized) before it can have any effect on the target tissues.
It also has relatively poor water solubility, so it doesn't absorb easily into the body.
• Inhaled CBD (ex:Vaping): Bioavailability is higher as this avoids
metabolism by the liver.
However, duration of effect is fairly short.
We understand your concerns.
The cost of your treatment will depend on the dose delivered. The typical starting dose of 4 ml (26.4 mg) is
$225. Each additional 1 ml is +$25, so an 8 ml (52.8 mg) dose would be $325.
This cannot be predicted for any one individual, and also may be dose dependent. Some will experience
benefit for 1 to 2 weeks whereas others may achieve 5 or more weeks of improvement.
Prior history of allergy to CBD, pregnant or breastfeeding women, persons with a tendency to be hypotensive (chronic low blood pressure) may be at increased risk of headedness. Persons with active bacterial infections may experience more post treatment side effects due to the antibacterial effects of CBD, but can still receive treatment.
Potential Side Effects (Usually Mild). Some people may experience: fatigue or drowsiness (especially at high doses), dry mouth, diarrhea or upset stomach, changes in appetite or weight, dizziness or low blood pressure
Until you know how you respond to treatment, it is best to avoid high risk activities such as operating heavy machinery. Infrequently, some patients will experience drowsiness or a sense of euphoria, which could lead to
temporary impairment. Be sure to hydrate very well post infusion and avoid sedatives. including alcohol. for 12 hours.
Yes, there are hundreds of studies which have looked at the safety and benefits of CBD for a broad range of symptoms and medical conditions. However, the FDA has not evaluated the effects of CBD for any specific conditions. PICOIV CBD is not promoted to diagnose, treat, cure or prevent any disease.
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